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Directed Evolution of Enzymes for Bioorthogonal Chemistry Using Acid Chloride Proximity Labeling

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NIAID Data Ecosystem2026-05-10 收录
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MDA-MB-231 cells expressing BS2-TRFLE in different compartments (cytosol, mitochondria, nucleus) were labeled with pAC-2. Subsequent enrichment of labeled RNAs, PolyA capture and RNA-seq reveals RNA populations in those compartments. Overall design: Differentially Expressed Gene (DEG) analysis of transcripts enriched in different compartments

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2026-01-20
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