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Minimal evidence of inflammaging in naturalistic chimpanzee populations

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DataONE2026-02-27 更新2026-03-14 收录
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Objectives: Whereas chronic inflammation is a hallmark of aging in many human populations, inflammaging is reduced in groups characterized by frequent physical activity and diets low in processed foods. Since most biomarkers of inflammation require blood sampling, comparative data from our closest primate relatives have been derived from sedentary, captive primate populations, whose processed diets are uncharacteristic of the wild. Materials and Methods: We evaluated ageing profiles of inflammation and oxidative stress biomarkers derived from urine and serum samples in semi-free ranging chimpanzees (Pan troglodytes) living in two African sanctuaries (N=156 health checks, 73 individuals, ages 11-39 years), where diet and physical activity more closely approximate the wild condition than captive laboratory settings. We compared these to urinary markers from wild chimpanzees from Kanyawara, Kibale National Park, Uganda (N=1,849 time points, 50 individuals, ages 10-57 years), as well as pub..., See paper for all detailed methods for this dataset. , # Data from: Minimal evidence of inflammaging in naturalistic chimpanzee populations Dataset DOI: [10.5061/dryad.v15dv429v](https://doi.org/10.5061/dryad.v15dv429v) ## Description of the data and file structure This data set consists of one data file (.xlsx format) reporting urinary and/or serum markers of inflammation from sanctuary-living and wild chimpanzees, as reported in the associated manuscript. There is a key tab in the file defining each variable reported in the main data tab, also reported below. ### Files and variables #### File: DATA_Cole_etal_chimpanzee_inflammation.xlsx **Description:** urinary and serum markers of inflammation from chimpanzees. ##### Variables | ***Variable*** | ***Description*** | | :----------..., ,
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2026-03-03
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