Expression data for participants in iWITH study at screening visit. Expression data for participants in iWITH study at screening visit

A cross sectional study using data collected at the time of liver biopsy, the final eligibility assessment for participation in iWITH (NCT01638559), an immunosuppression withdrawal trial. Microarrays were used to understand the gene expression profile differences among the three histological clusters (Cluster 1, Cluster 2 and Cluster 3) Overall design: RNA samples (n=151) were extracted from cryopreserved liver tissue samples using TRIzol and hybrid-ized onto Affymetrix Human Genome U219 96-array plates. We performed quality control using AffyPLM and excluded samples with a Normal-ized Unscaled Standard Error >1.05, resulting in 133 evaluable arrays.