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Transcriptional profiling of murine porcine-pancreatic elastase-induced abdominal aortic aneurysm at day 7, with parallel miRNA profiling and miR-24 in vivo modulation.

NIAID Data Ecosystem2026-03-07 收录

主动脉瘤分子机制

转录组与miRNA调控

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA221774 数据链接链接失效反馈

官方服务：

资源简介：

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

应用场景：

创建时间：

2013-09-27

主动脉瘤分子机制

NOTCH1基因功能

Ascending aortic aneurysms (AscAA) are a life-threatening disease whose molecular basis is poorly understood. Mutations in NOTCH1 have been linked to bicuspid aortic valve (BAV), which is associated w

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Table1_Identification of MEDAG and SERPINE1 Related to Hypoxia in Abdominal Aortic Aneurysm Based on Weighted Gene Coexpression Network Analysis.DOCX

主动脉瘤分子机制

基因靶点药物预测

Purpose: Abdominal aortic aneurysm (AAA) is a severe cardiovascular disease that often results in high mortality due to sudden rupture. This paper aims to explore potential molecular mechanisms and ef

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Transcriptomics provides novel insights into the regulatory mechanism of lncRNA HIF1A-AS1 on VSMCs. Transcriptomics provides novel insights into the regulatory mechanism of lncRNA HIF1A-AS1 on VSMCs

血管平滑肌细胞

主动脉瘤分子机制

In current study, using a lentivirus-based expression system, we observed that overexpressing HIF1A-AS1 successfully promoted apoptosis, significantly altered cell cycle distribution and greatly facil

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Data_Sheet_1_Postnatal Smad3 Inactivation in Murine Smooth Muscle Cells Elicits a Temporally and Regionally Distinct Transcriptional Response.PDF

主动脉瘤分子机制

平滑肌细胞转录调控

Heterozygous, loss of function mutations in positive regulators of the Transforming Growth Factor-β (TGF-β) pathway cause hereditary forms of thoracic aortic aneurysm. It is unclear whether and how th

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Table_3_Common molecular mechanism and immune infiltration patterns of thoracic and abdominal aortic aneurysms.xlsx

主动脉瘤分子机制

免疫浸润生物标志物

BackgroundAortic disease (aortic aneurysm (AA), dissection (AD)) is a serious threat to patient lives. Little is currently known about the molecular mechanisms and immune infiltration patterns underly

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