Mutations acquired by evolved clones identified through whole genome re-sequencing (WGS).

Mutations in intergenic regions have the two flanking genes listed (e.g., clpX/lon). SNPs are represented by an arrow between the ancestral and the evolved nucleotide. Whenever a SNP gives rise to a non-synonymous mutation the amino acid replacement is also indicated. The symbol Δ means a deletion. For intergenic mutations, the numbers in the Mutation row represent nucleotides relative to each of the neighboring genes, here + indicates the distance downstream of the stop codon of a gene and − indicates the distance upstream of the gene, that is relative to the start codon. Insertions of IS elements are denoted by the specific IS element followed by the number of repeated bases caused by its insertion.