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Crystal structure of Trichinella spiralis thymidylate synthase complexed with dUMP

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Protein Data Bank Japan2024-01-10 更新2026-03-21 收录
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Crystal structure of Trichinella spiralis thymidylate synthase complexed with dUMP Descriptor: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, GLYCEROL, ... Authors: Dowiercial, A, Jarmula, A, Rypniewski, W, Fraczyk, T, Wilk, P, Rode, W. Deposit date: 2015-06-10 Release date: 2015-06-17 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Crystal structures of nematode (parasitic T. spiralis and free living C. elegans), compared to mammalian, thymidylate synthases (TS). Molecular docking and molecular dynamics simulations in search for nematode-specific inhibitors of TS. J. Mol. Graph. Model., 77, 2017

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2015-06-10
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