RNA sequencing of WT and AICDA KO iPCS clones
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https://www.ncbi.nlm.nih.gov/sra/SRP190136
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We report AICDA facilitates naïve pluripotency of mouse iPSCs by suppressing FGF/ERK signaling. In the absence of AICDA iPSCs fail to achive naïve pluripotent state and display chracteristics of EpiSCs and are primed for differentiation. Overall design: IPSC clones from WT and AICDA KO fibroblasts were reprogrammed using OSKM.
创建时间:
2019-10-09



