Transcription Factors Involved in DNA Demethylation During Human Cellular Development. Transcription Factors Involved in DNA Demethylation During Human Cellular Development
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA720888
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资源简介：
DNA methylation is an important epigenetic modification involved in the regulation of mammalian gene expression, with each type of cell developing a specific methylation profile during its differentiation. The enzymatic mechanisms of DNA methylation and demethylation are well understood; however, little is known about how cell-type-specific DNA methylation profiles are developed. Recently, a small subgroup of transcription factors (TFs) have been shown to promote DNA demethylation at their binding sites (e.g., RUNX1 reported by our group). Overall design: Bisulphite converted DNA from the 50 samples were hybridised to the Illumina Infinium 850K Human Methylation Beadchip
创建时间：
2021-04-09
