<b>Hijacking the miR-200a&c–Jagged1 Negative Feedback Loop Attenuates </b><b><i>Angiostrongylus cantonensis</i></b><b>-Induced Demyelinating Optic Neuritis via Notch Suppression</b>

This dataset supports the research article "Hijacking the miR-200a&c–Jagged1 Negative Feedback Loop Attenuates Angiostrongylus cantonensis-Induced Demyelinating Optic Neuritis via Notch Suppression". It contains: • miRNA and mRNA microarray data from mouse corpus callosum • qRT-PCR validation data for miR-200a&c and Notch pathway genes • Western blot protein expression data for Jagged1, Notch signaling components • Visual electrophysiology (VEP/ERG) recordings • Histopathology images (H&E, LFB staining) • Electron microscopy images of myelin ultrastructure • Immunofluorescence images of retinal ganglion cells and myelin • Primary oligodendrocyte precursor cell viability data • Dual-luciferase assay results validating miR-200a targeting of Jagged1 The data demonstrate how parasitic infection disrupts neural feedback homeostasis and the therapeutic potential of miRNA intervention. Data are organized by figure panels from the associated publication.