Genome-wide RNA expression analysis of mouse spleens in parent-into-F1 lupus immune response

Analysis of whole spleen tissue expression signature in divergent responses from two parent-into-F1 lupus mouse model systems. The hypothesis is that strain differences of CD4 T cells exhibit difference lupus-inducing proclivity. Total RNA obtained from recipient mouse spleen at day 14 post-engraftment were profiled by Illumina BeadArray expression analysis