Sitagliptin is an antidiabetic drug that inhibits dipeptidyl peptidase-4 enzyme. This study aimed to investigate the antinociceptive and anti-inflammatory effects of sitagliptin in formalin and carrag
1Values are means ± SEM (n = 6/TNBS-treated mice/dietary group). Data were analyzed by two-way ANOVA (main effects: diet and treatment). For all genes, only the effect of diet is shown (P≤0.05). Value
The glucocorticoid receptor (GR) acts both as a transcription factor itself on genes carrying GR response elements (GREs) and as a modulator of other transcription factors. Using mice with a mutation
Comparison of stroke volume, heart rate, cardiac output, and oxygen consumption (VO2) in mice at baseline (t = 0) and 6 h after receiving vehicle, low- (1 µg/gBW), or high- (10 µg/gBW) dose LPS. Data