Crystal structure of human lysosomal acid-alpha-glucosidase, GAA, in complex with iminosugar compound 4k
收藏Protein Data Bank Japan2025-10-08 更新2026-04-19 收录
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Crystal structure of human lysosomal acid-alpha-glucosidase, GAA, in complex with iminosugar compound 4k Descriptor: (2~{R},3~{R},4~{R},5~{S})-2-(2-hydroxyethyl)-2-(hydroxymethyl)piperidine-3,4,5-triol, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Sulzenbacher, G, Roig-Zamboni, V, Moracci, M, Parenti, G, Py, S. Deposit date: 2024-09-18 Release date: 2025-10-01 Last modified: 2025-10-08 Method: X-RAY DIFFRACTION (1.8 Å) Cite: C -Branched Iminosugars as Selective Pharmacological Chaperones of Lysosomal alpha-Glucosidase for the Treatment of Pompe Disease. J.Med.Chem., 68, 2025
创建时间：
2024-09-18
