Effect of Omomyc on the in vivo growth of melanomas
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE227841
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资源简介：
Skin melanomas are highly aggressive and metastatic. Omomyc is the best MYC inhibitor currently available. We analysed the effect of Omomyc expression in a transgenic and inducible (upon Doxycycline addition) manner in melanoma cells in vivo in two different melanoma cell lines: A375 (mutated in BRAF), SkMel147 (mutated in NRAS). We used microarrays to detail the change in the gene expression programs induced by Omomyc on day 7. Melanomas from vehicle- or doxycycline-treated mice were excised, RNA extracted and hybridized on Affymetrix microarrays.
创建时间：
2023-04-11
