Emergence of pertactin-deficient Bordetella pertussis isolates in Spain.
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA667582
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资源简介：
Pertussis resurgence had been attributed to waning vaccine immunity and Bordetella pertussis adaptation to escape vaccine-induced immunity. Pertactin-deficient strains are highly prevalent in countries that use acellular vaccines (ACV), suggesting strong ACV-imposed selection of circulating bacteria. To corroborate this hypothesis in our geographical area, we provide pertussis epidemiologic data and molecular characterization of B. pertussis isolates from Spain, during 1986-2019.
创建时间：
2020-10-06
