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Lewis Base-Promoted Rearrangement of Allylic Cyanohydrins: Construction of Functionalized Nitriles Bearing 1,3-Diketone Moieties

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NIAID Data Ecosystem2026-03-09 收录
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https://figshare.com/articles/dataset/Lewis_Base_Promoted_Rearrangement_of_Allylic_Cyanohydrins_Construction_of_Functionalized_Nitriles_Bearing_1_3_Diketone_Moieties/2232823
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资源简介:
A novel Lewis base-promoted rearrangement of allylic cyanohydrins has been developed, in which the cyano group was rearranged, directly coupled with the generation of new functional groups. This protocol provides a unique and facile way to prepare highly functionalized nitriles bearing 1,3-diketone moieties under mild reaction conditions. Furthermore, the synthetic transformations of the functionalized products have also been demonstrated.
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2014-11-21
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