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Copper-Catalyzed Aerobic Intramolecular Carbo- and Amino-Oxygenation of Alkynes for Synthesis of Azaheterocycles

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Figshare2016-02-21 更新2026-04-29 收录
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https://figshare.com/articles/dataset/Copper_Catalyzed_Aerobic_Intramolecular_Carbo_and_Amino_Oxygenation_of_Alkynes_for_Synthesis_of_Azaheterocycles/2525491
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A synthetic method of highly substituted quinolines has been developed from N-(2-alkynylaryl)enamine carboxylates under Cu-catalyzed aerobic conditions via intramolecular carbo-oxygenation of alkynes. This strategy was further applied for N-alkynylamidines for amino-oxygenation of alkynes, leading to imidazole and quinazoline derivatives.
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2016-02-21
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