Here we describe a new class of immunostimulatory short duplex RNAs that potently induce production of type I interferon (IFN-I), and particularly IFN-β, in a wide range of human cell types via end-to
aNumbering according to H3 in parentheses, IVPI (intravenous pathogenicity index), HB (hemadsorbing site), aa (amino acids) PL (PL motif is referred as PDZ-binding motif at the C-terminal end of the N
In order to eliminate the disadvantages of the state of the art, an object of the invention is to cause permanent destruction in the structure and the function of the virus itself, owing to the tissue
Chronic HCV infection is characterized by several immunological alterations, such as the accumulation of suppressor cells and of hyperactivated T lymphocytes. However, it is unclear whether direct-act
