Crystal structure of HCV NS3/4A protease in complex with NR02-08
收藏Protein Data Bank Japan2023-10-18 更新2026-04-19 收录
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Crystal structure of HCV NS3/4A protease in complex with NR02-08 Descriptor: (1R,2R)-2-fluorocyclopentyl {(2R,4S,6S,12Z,13aS,14aR,16aS)-2-[(7-methoxy-3-methylquinoxalin-2-yl)oxy]-14a-[(1-methylcyclopropane-1-sulfonyl)carbamoyl]-5,16-dioxo-1,2,3,5,6,7,8,9,10,11,13a,14,14a,15,16,16a-hexadecahydrocyclopropa[e]pyrrolo[1,2-a][1,4]diazacyclopentadecin-6-yl}carbamate, 1,2-ETHANEDIOL, NS3/4a protease, ... Authors: Zephyr, J, Schiffer, C.A. Deposit date: 2021-04-29 Release date: 2022-03-09 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.43 Å) Cite: Deciphering the Molecular Mechanism of HCV Protease Inhibitor Fluorination as a General Approach to Avoid Drug Resistance. J.Mol.Biol., 434, 2022
创建时间：
2021-04-29
