Id2

ENCODES a protein that exhibits RNA polymerase II-specific DNA-binding transcription factor binding (ortholog); transcription regulator inhibitor activity (ortholog); transmembrane transporter binding (ortholog); INVOLVED IN cellular response to follicle-stimulating hormone stimulus; negative regulation of gene expression; negative regulation of transcription by RNA polymerase II; PARTICIPATES IN hypoxia inducible factor pathway; transforming growth factor-beta superfamily mediated signaling pathway; ASSOCIATED WITH Spinal Cord Injuries; Vascular System Injuries; acute myeloid leukemia (ortholog); FOUND IN chromatin; cytoplasm; nucleus; INTERACTS WITH 1,3,5-trinitro-1,3,5-triazinane; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine

编码一种具有RNA聚合酶II特异性DNA结合转录因子结合（同源）特性的蛋白质；转录调控抑制剂活性（同源）；跨膜转运蛋白结合（同源）；参与对促卵泡激素刺激的细胞响应；基因表达负调控；由RNA聚合酶II介导的转录负调控；参与缺氧诱导因子途径；转化生长因子-β超家族介导的信号通路；与脊髓损伤、血管系统损伤以及急性髓系白血病（同源）相关；存在于染色质、细胞质和细胞核中；与1,3,5-三硝基-1,3,5-三氮杂环烷、17α-乙炔雌二醇以及2,3,7,8-四氯二苯并-对氧杂蒽等物质相互作用。