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Crystal structure of PLK1 in complex with TAK-960

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Protein Data Bank Japan2024-02-28 更新2026-03-21 收录
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Crystal structure of PLK1 in complex with TAK-960 Descriptor: 4-[(9-cyclopentyl-7,7-difluoro-5-methyl-6-oxo-6,7,8,9-tetrahydro-5H-pyrimido[4,5-b][1,4]diazepin-2-yl)amino]-2-fluoro-5-methoxy-N-(1-methylpiperidin-4-yl)benzamide, ACETATE ION, Serine/threonine-protein kinase PLK1, ... Authors: Hosfield, D.J, Skene, R.J. Deposit date: 2013-02-07 Release date: 2013-05-29 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Discovery of TAK-960: An orally available small molecule inhibitor of polo-like kinase 1 (PLK1). Bioorg.Med.Chem.Lett., 23, 2013

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2013-02-07
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