Data associated with "Effects of M. tuberculosis and HIV-1 infection on in vitro blood-brain barrier function" paper
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READ ME<br>---Below is all the information you will need to understand the raw data associated with the paper:<br>**Effects of M. tuberculosis and HIV-1 infection on in vitro blood-brain barrier function***Alizé Proust, Katalin A. Wilkinson, Robert J. Wilkinson* <br>---**Figure 1 and Additional file 1:**This folder contains all data used for Figure 1 and Additional file 1.The file names indicate the purpose of the experiment (HIV infection, Mtb entry of Mtb growth) and the cell type (astrocytes, hCMEC/d3, HBVP or HMC3).Each file contains all the data organised per experiment (TB-HIV#1 to TB-HIV#7).<br>**Figure 2:**This folder contains all data used for Figure 2.- Figure 2A-B - Dextran-Rhodamine : it includes fluorescence readings of dextran rhodamine B per experiment at 2 and 6 days post-infection (TB-HIV#4 to TB-HIV#12)- Figure 2C-D - CFU: it includes CFUs count per experiment at 2 and 6 days post-infection (TB-HIV#4 to TB-HIV#12).<br>**Figure 3:**This folder contains all data used for Figure 3.The file names indicate the cell type (astrocytes, hCMEC/d3, HBVP or HMC3).Each file contains all the data organised per experiment (TB-HIV#1 to TB-HIV#15).<br>**Figure 4 and Additional file 5:**This folder contains all data used for Figure 4 and Supplementary Figure 5.- Subfolder Figure 4A-D : it includes the absorbance readings per cell type (TB-HIV#1 to TB-HIV#7).- Subfolder Figure 4E-H (and Additional file 5): it includes the luminescence readings per cell type. Each file contains all the data organised per experiment (TB-HIV#1 to TB-HIV#7).The file names indicate the type of experiment (MTS assay or ROS assay) and the cell type.<br>**Figure 5:**This folder contains all data used for Figure 5.- Figure 5A-B - Astrogliosis: it contains all the qPCR data organised per experiment (TB-HIV#1 to TB-HIV#7).- Subfolder Figure 5C-H: it includes the fluorescence readings of glutamate organised per cell type (astrocytes, hCMEC/d3, HBVP or HMC3). Each file contains all the data organised per experiment (TB-HIV#1 to TB-HIV#12).<br>**Figure 6 and Additional file 7:**This folder contains all Luminex data in pg/mL and stats used for Figure 6 and Additional file 7.The file names indicate the cell type (astrocytes, hCMEC/d3, HBVP or HMC3).Each file contains all the data organised per cytokine.<br>**Additional file 4:**This folder contains all data used for Additional file 4.it contains all the qPCR data organised per experiment (TB-HIV#1 to TB-HIV#6).<br>**Additional file 6:**This folder contains all data used for Additional file 6. it contains all the qPCR data organised per cell type (astrocytes, hCMEC/d3, HBVP or HMC3).Each files contains all the qPCR data organised per experiment (TB-HIV#1 to TB-HIV#6).<br><br>
提供机构:
The Francis Crick Institute
创建时间:
2024-08-29



