Associations of serum uric acid with cardiovascular disease risk factors: a retrospective cohort study in Southeastern China

Objective: To evaluate the associations between serum uric acid (SUA) levels and cardiovascular disease (CVDs) risk factors, focusing on potential sex-specific differences.
Design: A retrospective cohort study.
Setting: A large community-based survey was conducted every two years from 2010 to 2018 in Hangzhou, Zhejiang Province, Southeastern China.
Participants: 6119 participants aged 40 years and above who underwent at least three times of physical examinations were enrolled.
Methods: Participants were categorized into four groups (Q1-Q4) based on baseline SUA quartiles within the normal range, with hyperuricemia (HUA) as the fifth group. The Q1 was the reference. By stratifying participants by gender, the relationships between SUA levels and systolic blood pressure (SBP), diastolic blood pressure (DBP), fasting blood glucose (FBG), and total cholesterol (TC) were investigated using linear regression models in the generalized estimating equation (GEE). Additionally, the associations o..., Each participant was required to complete an in-person interview by a trained nurse using a standardized questionnaire, which included information related to demographic characteristics (age and sex) and the medical history (disease and drug history of hypertension, diabetes, dyslipidemia). Values of weight and height were measured using a calibrated scale and a stadiometer. BP was measured using a calibrated mercury sphygmomanometer. Two consecutive measurements were taken and recorded, with a 2-minute break across the two measurements.  The final value was calculated as the average of the two readings. Prior to venous blood sample collection, all participants were required to fast for at least eight hours. Serum creatinine, SUA, FBG, and TC for each participant were measured using standard clinical laboratory methods. The normality of continuous variables’ distribution was assessed using the Shapiro-Wilk tests. Continuous variables with normal distribution are presented as the mean ± ..., , # Associations of serum uric acid with cardiovascular disease risk factors: a retrospective cohort study in Southeastern China

This dataset provides information on serum uric acid levels and cardiovascular disease risk factors, as well as basic demographic information.

## Description of the data and file structure

The dataset is structured in a tabular format with the following columns:

* ID: Unique identifier for each participant
* Age: Age of the participant in years
* Sex: Gender of the participant (1.Male /2.Female)
* BMI: Body Mass Index of the participant
* SBP/DBP: Blood pressure readings of the participant (Systolic/Diastolic)
* FBG: Fasting blood glucose of participants of the participant
* TC: Cholesterol level of the participant
* Cr: Serum creatinine of the participants
* GFR: Glomerular filtration rate of participants
* UA: Measurement of serum uric acid level in the participant's blood
* Times: Number of medical follow-up visits for participants
-hypertension:Parti...