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Smo and Ets-2 signaling in fibroblasts effects gene expression

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE61707
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These experiments aim determine the effects of Smo and Ets-2 signaling on fibroblast gene expression. To achieve this, we used a genetic model in which Smo or Ets-2 was conditionally deleted in stromal fibroblasts in a Kras-driven mouse model ofpancreatic cancer. We isolated fibroblasts from pancreata mice with either wild type, Smo null, or Ets-2 null fibroblasts.
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2019-02-11
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