PCOSFMT

Dysbiosis of the microbiome is a key hallmark of polycystic ovary syndrome (PCOS). However, the interaction between the host and microbiome and its relevance with the pathogenesis of PCOS remains unclear. To evaluate the role of commensal gut microbiome in PCOS, we gavaged germ free mice with the fecal microbiota from patients with PCOS or healthy individuals, and evaluated PCOS phenotype in the recipient mice.