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RNA-sequencing of stably engrafted miR-99 KD LSKs

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NIAID Data Ecosystem2026-04-29 收录
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We FACS-purified GFP+ LSK cells from mice transplanted with stably engrafted miR-99 KD and Scr HSCs and performed RNA-sequencing, demonstrating miR-99 KD results in significant depletion of hematopoietic stem cell gene expression signature and induces a differentiated progenitor gene expression signature. Overall design: FACS purification of Scr and miR-99 KD LSKs from 2 mice in each group

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2021-07-25
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