Sex-aware genomic resources - Genome files

The aim of this resource is to provide researchers a set of genomes for sex-aware study. Current genomes may be suboptimal in read detection, due to the fact that some sequences are shared between X and Y chromosomes (PAR regions, XTR and other fine-grained regions). Therefore, to improve read alignment accuracy, the best strategy set is to map reads to XX or XY-adapted genomes depending on the sample karyotype. This resource includes genome .fa files of several assemblies (human GRCh38 and GRCh37 from ensembl, and T2T from UCSC; mouse GRCm39 and GRCm38 from ensembl) ready for use to create aligner indexes.