Crystal structure of trimethoprim-resistant type II dihydrofolate reductase in complex with a bisbenzimidazole inhibitor
收藏Protein Data Bank Japan2023-10-11 更新2026-03-21 收录
下载链接：
https://pdbj.org/mine/summary/6nxz
下载链接
链接失效反馈官方服务：
资源简介：
Crystal structure of trimethoprim-resistant type II dihydrofolate reductase in complex with a bisbenzimidazole inhibitor Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, 2-[4-[(2~{R})-4-[4-(6-carboxy-1~{H}-benzimidazol-2-yl)phenoxy]-2-oxidanyl-butoxy]phenyl]-1~{H}-benzimidazole-5-carboxylic acid, Dihydrofolate reductase type 2, ... Authors: Yachnin, B.J, Berghuis, A.M. Deposit date: 2019-02-10 Release date: 2019-05-29 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Structure-Based Design of Dimeric Bisbenzimidazole Inhibitors to an Emergent Trimethoprim-Resistant Type II Dihydrofolate Reductase Guides the Design of Monomeric Analogues. Acs Omega, 4, 2019
创建时间：
2019-02-10
