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Dysfunction of 5-methylcytosine oxidases and the Polycomb protein RYBP leads to widespread DNA hypermethylation and cell transformation [WGBS]

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NIAID Data Ecosystem2026-05-01 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE208688
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资源简介:
We inactivated RYBP, YAF2, TET1, TET2, and TET3 in bronchial cells, individually and in combination, and observed widespread DNA methylation by performing whole genome bisulfite sequencing. Comparative DNA methylation analysis of WGBS data in HBEC3 defective cell (Control cells, RKO, YKO, TET2 KO, TET3KO, TET2/TET3 DKO, TET123 TKO and TET123/RYBP QKO )
创建时间:
2023-10-05
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