EGFR kinase domain complexed with a quinazoline inhibitor- GW572016
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https://pdbj.org/mine/summary/1xkk
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EGFR kinase domain complexed with a quinazoline inhibitor- GW572016 Descriptor: Epidermal growth factor receptor, N-{3-CHLORO-4-[(3-FLUOROBENZYL)OXY]PHENYL}-6-[5-({[2-(METHYLSULFONYL)ETHYL]AMINO}METHYL)-2-FURYL]-4-QUINAZOLINAMINE, PHOSPHATE ION Authors: Wood, E.R, Truesdale, A.T, McDonald, O.B, Yuan, D, Hassell, A, Dickerson, S.H, Ellis, B, Pennisi, C, Horne, E, Lackey, K, Alligood, K.J, Rusnak, D.W, Gilmer, T.M, Shewchuk, L.M. Deposit date: 2004-09-29 Release date: 2004-12-07 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.4 Å) Cite: A unique structure for epidermal growth factor receptor bound to GW572016 (Lapatinib): relationships among protein conformation, inhibitor off-rate, and receptor activity in tumor cells. Cancer Res., 64, 2004
创建时间：
2004-09-29
