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Measure Celluar Force Using DNA-based Tension Probes: From Ensemble to Single-Molecule Studies - Source Data.

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https://figshare.com/articles/dataset/Measure_Celluar_Force_Using_DNA-based_Tension_Probes_From_Ensemble_to_Single-Molecule_Studies_-_Source_Data_/29979346
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The source data of a protocol for the use of two advanced DNA-based tension probes, the reversible shearing DNA-based tension probe (RSDTP) and ForceChrono probe, which provide powerful tools for studying mechanotransduction in living cells. ·This protocol describes the use of two advanced DNA-based tension probes, the reversible shearing DNA-based tension probe (RSDTP) and ForceChrono probe, which provide powerful tools for studying mechanotransduction in living cells. Compare to other probes, RSDTP enables reversible and repeatable measurements to be made across a wide range of forces, while ForceChrono probes capture force duration and loading rate, providing essential insights into the temporal dynamics of single-molecule force transmission.
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2025-08-25
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