Cancer Cell Line Encyclopedia

The Cancer Cell Line Encyclopedia project is a collaboration between the Broad Institute, and the Novartis Institutes for Biomedical Research and its Genomics Institute of the Novartis Research Foundation to conduct a detailed genetic and pharmacologic characterization of a large panel of human cancer models, to develop integrated computational analyses that link distinct pharmacologic vulnerabilities to genomic patterns and to translate cell line integrative genomics into cancer patient stratification. The CCLE provides public access to genomic data, analysis and visualization for about 1000 cell lines.

癌症细胞系百科全书项目是由Broad研究所与诺华生物医学研究学院及其诺华研究基金会基因组学研究所共同发起的一项合作项目。该项目旨在对大量人类癌症模型进行详尽的遗传学和药理学特征描述，开发将不同的药理学易感性与其基因组模式相联系的集成计算分析，并将细胞系整合基因组学转化为癌症患者的分类策略。CCLE（癌症细胞系百科全书）向公众提供约1000种细胞系的基因组数据、分析和可视化访问。