RNA Sequencing of Mrp8-Cre;TGFbR2-fl/fl Lung Neutrophils
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE198654
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Purpose: The goal of this study is to examine how the specific loss of TGFbR2 (under Mrp8 promoter for Cre recombinase) changes the transcriptome of neutrophils in the lung compared to their wildtype littermates. Lung neutrophils from Mrp8-Cre;TGFbR2-fl/fl (mutant) or Cre-negative TGFbR2-fl/fl littermate control mice (wt) [B6.Cg-Tg(S100A8-cre,-EGFP)1Ilw/J x B6;129-Tgfbr2tm1Karl/J] (N=3 per group) were purified by flow cytometry-assisted cell sorting, then submitted for bulk RNA sequencing.
创建时间：
2025-01-11
