Additional file 2: Table S1. of Identification of common oncogenic and early developmental pathways in the ovarian carcinomas controlling by distinct prognostically significant microRNA subsets

The 13-miRNA subset from K-means. Table S2. The 100 survival significant miRNAs and results of the DDSS-1D, DDSS-2D and SWVg analyses. TCGA dataset was analysed. The 10 survival significant miRNAs belonging to the 13 miRNA subset selected by K-means analysis are highlighted. Table S3. The 25-miR subset selected by DDSS-1D with ten-fold cross validation. Table S4. The frequency of miRs in DDSS-2D miR pairs. The miRNAs which was reported in 13 miRNAs selected by K-means analysis were highlighted in yellow cell. Table S5. 28 miRNAs which display the patterns with three groups in DDSS-1D. Table S6. Analysis of 19-miRNA prognostic signature. Significant clusters generated from DAVID functional annotation tools. Each DAVID annotation cluster represents one biological theme by grouping similar annotation terms according to the common genes shared by them. Table S7. Association analysis of clinical indicators with groups separated by 19 miRNAs from SWV based on DDSS-1D. Table S8. Seventeen survival-significant miRNAs in Shih et al signature [5]. Table S9. Wald P-values of 4 significant miRNA in TCGA dataset, supported by independent dataset [5]. Table S10. Three miRNA survival prediction signatures of HG-SOC. Table S11. Comparison of the 19-miRNA survival prediction signature with other miRNA-based survival prediction signatures of HG-SOC. Table S12. Concensus subset of survival significant miRNAs. Table S13. DDSS-1D-based selection of the 31 miRNAs and SWVg analysis. Table S14. Interactions between miRNAs and predicted direct target mRNAs found in 36 mRNA HG-EOC prognostic classifier. Table S15. Significant signaling pathways (by DIANA-mirPath v.2 software) targeting by the miRNA subsets belonging to five miRNA signatures. The common pathways shared by miRNA signatures from K-means, DDSS-D1, DDSS-D2 and SWVg analyses are marked in boldface. Table S16. Initial data lists for for miRPath-7.3 analysis, the number target genes and the target identification methods. Table S17. Common signaling pathways. Table S18. Neurotrophin signalling pathway: Updated lists of the miRNAs refereeing to the 19-miRNA (19_mir_N), 21-miRNA (21_mir_N) and 31miRNA (31_mir_N) prognostic signatures and their characteristics. Table S19. Neurotrophin signaling pathway data (miRNAs, mRNA). Table S20. Number of miRNAs interacting with a target mRNA associated with gene encoding neurophilin signaling pathway. Table S21. Tarbase Experimentally Supported Interactions for miRNAs. (XLS 400 kb)