Integrin AlphaVBeta3 ectodomain bound to antagonist TDI-4161

Integrin AlphaVBeta3 ectodomain bound to antagonist TDI-4161 Descriptor: (2S)-2-[(1,3-benzothiazole-2-carbonyl)amino]-4-{[5-(1,8-naphthyridin-2-yl)pentanoyl]amino}butanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: van Agthoven, J, Arnaout, M.A. Deposit date: 2018-09-24 Release date: 2019-09-25 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (3.005 Å) Cite: Novel Pure alphaVbeta3 Integrin Antagonists That Do Not Induce Receptor Extension, Prime the Receptor, or Enhance Angiogenesis at Low Concentrations Acs Pharmacol Transl Sci, 2, 2019