Crystal structure of human apoptosis-inducing factor (AIF) bound to the fused N-terminal domain of CHCHD4

Crystal structure of human apoptosis-inducing factor (AIF) bound to the fused N-terminal domain of CHCHD4 Descriptor: 1,2-ETHANEDIOL, Apoptosis-inducing factor 1, mitochondrial,Mitochondrial intermembrane space import and assembly protein 40, ... Authors: Brosey, C.A, Tainer, J.A. Deposit date: 2023-12-29 Release date: 2025-01-08 Last modified: 2025-03-05 Method: X-RAY DIFFRACTION (2.3 Å) Cite: NADH-bound AIF activates the mitochondrial CHCHD4/MIA40 chaperone by a substrate-mimicry mechanism. Embo J., 44, 2025