Gene expression modification in lungs of rats exposed to carbon black by inhalation

In this work we study the pulmonary toxicological properties of Printex using molecular toxicological approache. For this, we exposed Sprague Dawley rats by inhalation. Lung samples have been collected up to 180 days after the end of exposure and transcriptomics analysis were performed.本研究采用分子毒理学方法，探究Printex的肺部毒理特性。为此，我们通过吸入途径对斯普拉格-道利（Sprague Dawley）大鼠进行染毒。于染毒结束后长达180天的时间内采集肺组织样本，并开展转录组学分析。