Enrichments of proteins with and without protein-binding domains (PBDs), in the interactor lists of the EPDs*.

*As for Table 1.**Proteins containing PBDs are those containing predicted coiled-coil regions or protein-binding domains defined specifically as such, in InterPro (see Methods for details). The enrichment of proteins containing PBDs in the list of their own interactors is very highly significant (P = 4e−52).†As for Table 1.