Selective Release of Aromatic Heterocycles from Ruthenium Tris(2-pyridylmethyl)amine with Visible Light
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https://figshare.com/articles/dataset/Selective_Release_of_Aromatic_Heterocycles_from_Ruthenium_Tris_2_pyridylmethyl_amine_with_Visible_Light/2092507
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资源简介：
Three complexes of the general formula
[Ru(TPA)L2](PF6)2 [TPA = tris(2-pyridylmethyl)amine],
where L = pyridine (1), nicotinamide (2),
and imidazole (3), were prepared and characterized spectroscopically.
X-ray crystallographic data were obtained for 1 and 3. Complexes 1–3 show strong
absorption in the visible region and selective release of heterocycles
upon irradiation with visible light. Time-dependent density functional
theory calculations are consistent with the presence of singlet metal-to-ligand
charge-transfer bands in the visible region in 1–3. Caged heterocycles 1–3 are highly stable in solution in the dark, including in cell growth
media. Cell viability data show no signs of toxicity of 1–3 against PC-3 cells at concentrations up to
100 μM under light and dark conditions, consistent with Ru(TPA)
acting as a nontoxic and effective photocaging group for aromatic
heterocycles.
创建时间：
2016-02-12
