We present an agent-based model (ABM) to simulate a hepatic inflammatory response (HIR) in a mouse infected by Salmonella that sometimes progressed to problematic proportions, known as “sepsis”. Based
Processed experimental data, model initial conditions, and simulation outputs supporting the manuscript: “Mechanistic pathway modeling reveals how IL-10 generates pleiotropic immune responses.” This
In general, this data has been generated using a quantitative biochemical peptide-HLA interaction assay (see PMID: 12135423). The HLA class I molecules have been selected to cover the known HLA supert