Profiling the effect of Nafcillin on HA-MRSA D712 using bacteriological and physiological media
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE139141
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Vancomycin Intermediate Staphylococcus aureus (VISA) strain originated during the prolonged hospitalization, chronic infection and vancomycin treatment. The hospital acquired D712 VISA strain were subjected to various sub-inhibitory concentration of nafcillin in Cation Adjusted Mueller Hinton Broth (CA-MHB) and Roswell Park Memorial Institute (RPMI) medium. The MIC of has dropped from 256 ug/ml to 1ug/ml in CA-MHB and RPMI media respectively. The cells were harvested and expression profiling were measured using RNA sequencing at time point of 03 hours. Staphylococcus aureus were treated with various sub-inhibitory concentration of Nafcillin in CA_MHB and RPMI + 10% LB media.
创建时间：
2021-12-02
