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Identification of Genes Regulated by Peptidylarginine Deiminase (PAD) Catalyzed Histone Citrullination in Prolactinomas

NIAID Data Ecosystem2026-03-10 收录

蛋白瓜氨酸化

催乳素瘤分子机制

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA422458 数据链接链接失效反馈

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资源简介：

Identification of Genes Regulated by Peptidylarginine Deiminase (PAD) Catalyzed Histone Citrullination in Prolactinomas

应用场景：

创建时间：

2017-12-14

蛋白瓜氨酸化

受体信号通路

Estrogen receptor α (ER), a member of the nuclear hormone receptor superfamily, regulates transcriptional activity by ligand-dependent recruitment of cofactors which, in turn, locally alter chromatin

NIAID Data Ecosystem70

Histone citrullination in estrogen receptor signaling and breast cancer [ChIP-seq]

蛋白瓜氨酸化

乳腺癌表观遗传学

PAD2, one of a family of PAD enzymes that convert positively charged arginine residues on target proteins to neutrally charged citrulline, has been shown to play a role in estrogen signaling through i

NIAID Data Ecosystem40

Natural and molecular history of prolactinoma: insights from a Prlr -/- mouse model. Mus musculus

催乳素瘤分子机制

肿瘤动物模型

Mouse models of prolactinoma can be useful to better understand molecular mechanisms involved in abnormal lactotroph cell proliferation and secretion. We have previously developed a prolactin receptor

NIAID Data Ecosystem10

DataSheet_1_Characterization of Monoclonal Antibodies Recognizing Citrulline-Modified Residues.pdf

蛋白瓜氨酸化

单克隆抗体

BackgroundCitrullination is a post-translational protein modification linked to the occurrence and development of a variety of diseases. The detection of citrullinated proteins is predominately based

NIAID Data Ecosystem40

NET formation is a default epigenetic program controlled by PAD4 in apoptotic neutrophils. NET formation is a default epigenetic program controlled by PAD4 in apoptotic neutrophils

细胞死亡机制

蛋白瓜氨酸化

Neutrophil extracellular traps (NETs) counteract bacterial and fungal pathogens but can also promote thrombosis, autoimmunity, and sterile inflammation. The presence of citrullinated histones, generat

NIAID Data Ecosystem20

Identification of Genes Regulated by Peptidylarginine Deiminase (PAD) Catalyzed Histone Citrullination in Prolactinomas

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