An mRNA-encoded, long-lasting Interleukin-2 restores CD8+ T cell neoantigen immunity in MHC class I-deficient cancers

Cd45Summit-IntgrAllgroups_finalUMAP_simplified_colorordered.RData contains all final result of the workflow (data integration and annotation) without subsetting the cell types into the different treatment groups.

Cd45Summit-IntgrAllgroups_finalUMAP_Only_CD8Tcells_subsetted.RData contains combined dataset of all present CD8+ T cell types (final UMAP, all annotated), which are subsetted into the four treatment groups.

Cd45Summit-IntgrAllgroups_finalUMAP_Only_ProlifMacros_subsetted.RData contains only the proliferating CD8+ T cells, which are subsetted into the four different treatment groups.

Cd45Summit-IntgrAllgroups_forJan_Macors_Gr1to4.RData contains only the combined macrophages of the dataset, subsetted into the four treatment groups.