TCF/LEF dependent and independent regulation of Wnt/beta-catenin transcription

ChEBI2018-11-02 更新2026-07-12 收录

Wnt信号通路调控

β-catenin转录机制

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-MTAB-7029 数据链接链接失效反馈

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TCF/LEF dependent and independent regulation of Wnt/beta-catenin transcription

创建时间：

2018-11-02

SOX transcription factors direct TCF-independent Wnt/beta-catenin transcription

Wnt信号通路调控

胚胎发育转录组学

We report ChIP-Seq experiments to profile the genomic binding dynamics of ß-catenin, SOX17, SOX2 and TCF/LEF TFs in definitive endoderm and neuromesodermal progenitor cells and RNA-Seq/ATAC-Seq exper

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Importance of RAD6B in activation of canonical WNT signaling in melanoma development

黑色素瘤分子机制

Wnt信号通路调控

We have demonstrated that RAD6B, a ubiquitin conjugating enzyme that is a principal component of translesion synthesis pathway, stabilizes and transcriptionally activates beta-catenin by lysine 63-lin

NIAID Data Ecosystem60

Wnt signaling promotes cell caudalization and inner ear differentiation in mouse stem cell-derived organoids

类器官分化

Wnt信号通路调控

Multiple time points and doses of Wnt activation were sampled. Data showed that precise Wnt modulation promote the cell caudalization and inner ear differentiation single cell RNA-sequencing data were

NIAID Data Ecosystem50

Expression data from Control or TRIB3-silenced HCT-8 cells. Expression data from Control or TRIB3-silenced HCT-8 cells

结直肠癌分子机制

Wnt信号通路调控

To determine the critical mediator of TRIB3-enhanced Wnt/beta-catenin signaling, we examined the expression profile of genes that might regulate Wnt/beta-catenin by using mRNA microarrays. Aberrant ac

NIAID Data Ecosystem60

TGFÃ-induced lncRNA LINC00313 activates Wnt signalling and promotes cholangiocarcinoma progression

胆管癌分子机制

Wnt信号通路调控

Cholangiocarcinoma (CCA) is a devastating liver cancer characterized by high aggressiveness and resistance to therapy, which results to poor prognosis. Signals imposed by oncogenic pathways, such as t

NIAID Data Ecosystem50

TCF/LEF dependent and independent regulation of Wnt/beta-catenin transcription

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