Expression data from early postnatal brain in autism model marmoset

Autism spectrum disorder (ASD) affects gene expression in early postnatal development. We used valproic acid (VPA)-induced ASD model marmosets. Gene expression in VPA-exposed and unexposed (UE) marmosets were analyzed at 0, 3 and 6 months (M). We revealed three groups of differentially expressed genes based on the temporal patterns of modulation. Tissues from three cortical areas (Brodmann area 8, 12, and TE) of UE and VPA marmosets were isolated. RNA was extracted and hybridized on custom-made microarrays. We sought to obtain differentially expressed genes at each age.