isoDTB-ABPP Cysteine Chemoproteomic Profiling for bigelovin
收藏国家人口健康科学数据中心2026-06-01 收录
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https://www.ncmi.cn/phda/dataDetails.do?id=CSTR:17970.11.A001G.202406.138.V1.0
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资源简介：
isoDTB-ABPP Cysteine Chemoproteomic Profiling was used to detect the targets of bigelovin in NLRP3 inflammasome activation. LPS and ATP induced bone marrow derived macrophages were adopted for the experiment in three biological replicates. Cell was treated with DMSO and bigelovin respectively. The cell lysate was incubated with IA-alkyne, followed by click reaction. The DMSO group was labeled by light isoDTB tags and the bigelovin group was labeled by heavy isoDTB tags.
提供机构：
北京蛋白质组研究中心
创建时间：
2024-06-11
