Additional file 1 of A novel small molecule, AS1, reverses the negative hedonic valence of noxious stimuli

Additional file 1: Database 1. Raw data from the drug screen. Raw data from the initial drug screen performed upon the Chembridge small molecule library. The first tab (labeled KEY) contains information about all of the individual drugs screened from this library, including data pertaining to the chemical structure (i.e., chemical formula, name, and molecular weight), location within the library (i.e., plate number and coordinates within the plate), and Chembridge ID number. All subsequent tabs are labeled with the number of the specific plate that was screened (i.e., 2 corresponds to Plate 2, 3 to Plate 3, etc.). These tabs contain the percentage of time individual fish spent in the 28.5°C temperature zone for control, AITC, and drug-treated conditions, as well as summary statistics (mean, s.e.m., and N) for all of these groups. Each pool contains the eight drugs within a single column of the plate; Pool 2 corresponds to Column 2, Pool 3 to Column 3, and so on. Though the drug library was contained in 96-well plates, only Columns 2-11 of each plate contained drugs, thus Pools 1 and 12 are absent from this screen.