Metal Free C–H Functionalization Enabled Diastereoselective Multicomponent Reaction of N‑Heterocycles to Fused Heteropolycycles
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https://figshare.com/articles/dataset/Metal_Free_C_H_Functionalization_Enabled_Diastereoselective_Multicomponent_Reaction_of_N_Heterocycles_to_Fused_Heteropolycycles/6901031
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资源简介：
A novel C–H functionalization
enabled multicomponent reaction
involving N-heterocycles, dinucleophile, and dipolarophile has been
developed. Direct α- and more challenging β-C(sp3)–H
functionalization of aliphatic N-heterocycles was achieved without
the use of metallic reagents and oxidants under either conventional
or microwave aided heating conditions. In a single operation, up to
five carbon–carbon and carbon–heteroatom bonds are formed
in a highly diastereoselective manner, providing the expeditious access
to the complex heteropolycycles.
创建时间：
2018-08-02
