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Crystal structure of the catalytic domain of human diphosphoinositol pentakisphosphate kinase 2 (PPIP5K2) in complex with AMPPNP and a substrate analog 5PA-IP5

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Protein Data Bank Japan2023-09-20 更新2026-03-21 收录
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Crystal structure of the catalytic domain of human diphosphoinositol pentakisphosphate kinase 2 (PPIP5K2) in complex with AMPPNP and a substrate analog 5PA-IP5 Descriptor: (2-oxo-2-{[(1s,2R,3S,4s,5R,6S)-2,3,4,5,6-pentakis(phosphonooxy)cyclohexyl]oxy}ethyl)phosphonic acid, Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2, MAGNESIUM ION, ... Authors: Wang, H. Deposit date: 2012-10-18 Release date: 2012-10-31 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.9 Å) Cite: First synthetic analogues of diphosphoinositol polyphosphates: interaction with PP-InsP(5) kinase. Chem.Commun.(Camb.), 48, 2012
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2012-10-18
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