Gene expression of splenocytes in collagen-induced arthritis (CIA) model between Wildtype and Stinggt/gt mice.. Gene expression of splenocytes in collagen-induced arthritis (CIA) model between Wildtype and Stinggt/gt mice.

To explore the effect of sting molecule in CIA model, we decided to performed microarray for study at how the difference in gene expression profiles between wildtype and Stinggt/gt mice. Overall design: We injected chicken collagen type II plus CFA intradermally to the mice. After two weeks of injection, mice were euthanasia and spleen were collected to perform microarray.