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Expression data of CD44 variant-positive and -negative cells derived from gastric cancer JSC153 cells

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NIAID Data Ecosystem2026-03-11 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE129747
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Cancer stem cells are subpopulation of cancer cells with highly tumorigenic and drug-resistant potential and are believed to contribute to the early phases of drug resistance. In gastric cancer, a population of cancer cells expressing splicing variants of a cell surface transmembrane glycoprotein, CD44, (CD44v), particularly CD44v9 containing variant exons 8–10, was shown to possess cancer stem cell properties. We sorted CD44v9-positive and -negative cells from patient-derived gastric cancer JSC15-3 cells and examined gene expression profile of the cells (JSC153CD44v9Plus, JSC153CD44v9Minus). We established patient-derived gastric cancer JSC15-3 cells, sorted CD44v9-positive and -negative cells by flow cytometry, and then obtained gene expression data (JSC153CD44v9Plus, JSC153CD44v9Minus).
创建时间:
2020-04-10
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